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eNMR Lab

Magnetic resonance is one of the most powerful methods to study nano- and microscale structure and dynamics. The information from nuclear or electronic spins helps to understand, predict and modify mechanical, chemical and medical functionality over a diverse range of applications. Understanding and manipulation of the spin interactions is becoming more and more detailed by new experimental and information technologies.


We use numerical models for electromagnetic and mechanical optimization of sensor (NMR probehead) design. The probeheads are particularly customized for applications in structural biology, heterogeneous catalyses and battery materials. In the process a new class of electrolytes for high energy batteries materialized and is a subject of intensive study. Biomedical research is related to inhibition of Alzheimer fibrillations by phytopharmacoids. Our software development is related to the reliability of metabolomics data processing, and applied for example on early characterization of cardiovascular problems and treatment monitoring. 

Research group of e-NMR

Head of the research group: Lead Research Scientist AGO SAMOSON
Members: Tiina Titma, Kalju Vanatalu, Andres Oss, Meelis Rohtmäe
Doctoral students: Molaiyan Palanivel, Irshad Mohammad

Topics and Competences
Keywords: micromechanics, radioengineering, technical ceramics, CAD, Alzheimer, NMR, MAS, metabolomics

NMR is a remarkably universal analytical method since essential spin interactions can be reliably calculated. The spectra allow in principle a 3D reproduction of the entire spin system and associated atoms/molecules, even a dynamics of it, given sufficient resolution and sensitivity.
The group develops NMR sensors-probeheads, notably to use the most sensitive nuclei-hydrogens, in locally viscous and solid environment. The most critical feature is rapid sample spinning. We were the first to reach rates beyond 120 kHz, getting presently over 150 kHz, which facilitates a practical inverse detection in solid state NMR. The immediate sensitivity increase is two orders of magnitude. The technology is applied in contemporary priority areas: biomedical research and development of F-ion batteries as a safer and more potent alternative for Li-based energy storage. The related key competences comprise CAD/CAM design, RF circuit modelling, technical ceramics processing and micro-machining.
In 2019 the group worked on development of NMR technologies and inhibition of fibril formation, related to Alzheimer disease.

Selected publications: