9.04.2021, 1:00 PM
Anna Cowart, "An Investigation of Noncovalently Bound Supramolecular Systems Through Case Studies of Oxacalixarenes and Iodo-triazoles"
Supervisor: Dr. Jasper Adamson, National Institute of Chemical Physics and Biophysics, Tallinn, Estonia
Co-supervisor: Prof. Riina Aav, School of Science, Tallinn University of Technology, Tallinn, Estonia
Opponents:
- Prof. Edvinas Orentas, Department of Organic Chemistry, Vilnius University, Vilnius, Lithuania
- Dr. Erki Enkvist, Institute of Chemistry, Faculty of Science and Technology, Tartu University, Tartu, Estonia
Summary
Noncovalent binding plays a key role in the self-assembly of chemical compounds and has found use in applications belonging to different fields of chemistry. Noncovalent interactions are utilized in materials that are applied in pharmaceutical industry and water purification technologies. The importance of noncovalent binding on its own has been an area of interest in organic chemistry and catalysis. The purpose of this PhD thesis is to investigate two different type of compounds– oxacalixarenes and iodo-triazoles, and their noncovalently bound supramolecular systems. In this PhD thesis, three oxacalixarene macrocycles were prepared and their interactions with different organic compounds investigated with the aim to evaluate the potential of the macrocycles as functional materials that can neutralize toxic organic compounds through noncovalent interaction driven encapsulation processes. Additionally, the correlation between the formation the specific type of noncovalent bond, halogen bond, and modified iodo-triazole structural properties was studied. The results of oxacalixarene-based materials and selective halogen bond donors presented in this thesis, will aid in the future development of technologies based on noncovalent binding.